The defender is prioritizing his fitness and has decided not to play in the upcoming matches against Italy and Belgium.
Per the French FA, coach Didier Deschamps and Fofana had a conversation about his fitness.
The player believes that rest is what he needs at present, after a long layoff last term.
A statement read: "After an exchange with Didier Deschamps, Wesley Fofana will finally remain at Chelsea's disposal and take advantage of the international break to follow a treatment protocol, linked to the injuries which kept him away from the pitch for a long time last season.
"Loic Badé (FC Seville) is called up for the first time to replace him."